Manchester United will take on debutants Granada in the Europa League quarter-finals.
Granada will be looking to continue their dream run against a United side who edged out AC Milan 2-1 on aggregate in the last-16.
Arsenal, the other remaining English club in the competition, take on Slavia Prague, who defeated Rangers at Ibrox 2-0 (3-1 on aggregate).
Elsewhere, 2017 runners-up Ajax take on Roma, the UEFA Cup runners-up in 1991.
Dinamo Zagreb, who shocked Tottenham in the quarter-finals by coming back from 2-0 down in the first leg to win 3-2 on Thursday night, will host Villarreal managed by former Gunners boss Unai Emery.
The earliest Manchester United and Arsenal could face each other is in the final.
The quarter-final first legs will take place on April 8 before the return matches on April 15. The semi-final first legs will be held on April 28 and the second legs on May 6.
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The Europa League final will take place at Gdansk Arena in Poland on May 26.
- FULL DRAW:
Quarter-finals
- Granada v Manchester United
- Arsenal v Slavia Prague
- Ajax v Roma
- Dinamo Zagreb v Villarreal
Semi-finals
- Granada/Manchester United v Ajax/Roma
- Dinamo Zagreb/Villarreal v Arsenal/Slavia Prague
Final
- Winner of semi-final 2 v Winner of semi-final 1
REMAINING EUROPA LEAGUE DATES
- Quarter-finals first legs: April 8
- Quarter-finals second legs: April 15
- Semi-finals first legs: April 29
- Semi-finals second legs: May 6
- Final: May 26 at Gdansk Arena, Poland